Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells

Induction of beta defensin 2 by NTHi requires TLR2 mediated MyD88 and IRAK-TRAF6-p38MAPK signaling pathway in human middle ear epithelial cells

<p>Abstract</p> <p>Background</p> <p>All mucosal epithelia, including those of the tubotympanium, are secreting a variety of antimicrobial innate immune molecules (AIIMs). In our previous study, we showed the bactericidal/bacteriostatic functions of AIIMs against variou...

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Main Authors: Park Rae-Kil, Andalibi Ali, Moon Sung K, Pan Huiqi, Woo Jeong-Im, Akopyan Arsen, Shimada Jun, Takeshita Tamotsu, Lee Haa-Yung, Kang Sung-Ho, Kang Shin-Seok, Gellibolian Robert, Lim David J
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/8/87

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http://www.biomedcentral.com/1471-2334/8/87

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