Src regulates the activity of the ING1 tumor suppressor.

Src regulates the activity of the ING1 tumor suppressor.

The INhibitor of Growth 1 (ING1) is stoichiometric member of histone deacetylase (HDAC) complexes and functions as an epigenetic regulator and a type II tumor suppressor. It impacts cell growth, aging, apoptosis, and DNA repair, by affecting chromatin conformation and gene expression. Down regulatio...

Full description

Bibliographic Details
Main Authors: Lisa Yu, Satbir Thakur, Rebecca Yy Leong-Quong, Keiko Suzuki, Andy Pang, Jeffrey D Bjorge, Karl Riabowol, Donald J Fujita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3621671?pdf=render

Internet

http://europepmc.org/articles/PMC3621671?pdf=render

Similar Items