Src regulates the activity of the ING1 tumor suppressor.
The INhibitor of Growth 1 (ING1) is stoichiometric member of histone deacetylase (HDAC) complexes and functions as an epigenetic regulator and a type II tumor suppressor. It impacts cell growth, aging, apoptosis, and DNA repair, by affecting chromatin conformation and gene expression. Down regulatio...
Main Authors: | Lisa Yu, Satbir Thakur, Rebecca Yy Leong-Quong, Keiko Suzuki, Andy Pang, Jeffrey D Bjorge, Karl Riabowol, Donald J Fujita |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3621671?pdf=render |
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