Intracellular PD Modelling (<i>PD</i><sub>i</sub>) for the Prediction of Clinical Activity of Increased Rifampicin Dosing
Increasing rifampicin (RIF) dosages could significantly reduce tuberculosis (TB) treatment durations. Understanding the pharmacokinetic-pharmacodynamics (PK−PD) of increasing RIF dosages could inform clinical regimen selection. We used intracellular PD modelling (<i>PD</i><s...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-06-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4923/11/6/278 |