Inhibitory effect of the melanocortin receptor agonist melanotan-II (MTII) on feeding depends on dietary fat content and not obesity in rats on free-choice diets

Inhibitory effect of the melanocortin receptor agonist melanotan-II (MTII) on feeding depends on dietary fat content and not obesity in rats on free-choice diets

Introduction: Conflicting data exist on sensitivity changes of the melanocortin system during diet-induced obesity. We hypothesized that melanocortin sensitivity depends on diet composition, in particular on the fat content rather than the level of obesity. The aim of this study was to determine the...

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Bibliographic Details
Main Authors: José eVan Den Heuvel, Leslie eEggels, Andrea evan Rozen, Eric eFliers, Andries eKalsbeek, Roger eAdan, Susanne E la Fleur
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Obesity
food intake
melanocortin
DIETS
saturated fat
liquid sugar
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00358/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00358/full

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