Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma

Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma

Retinal neuronal cell death underlies many incurable eye diseases such as retinitis pigmentosa (RP) and glaucoma, and causes adult blindness. We have shown that maintenance of ATP levels via inhibiting ATP consumption is a promising strategy for preventing neuronal cell death. Here, we show that bra...

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Bibliographic Details
Main Authors: Tomoko Hasegawa, Hanako Ohashi Ikeda, Sachiko Iwai, Yuki Muraoka, Tatsuaki Tsuruyama, Keiko Okamoto-Furuta, Haruyasu Kohda, Akira Kakizuka, Nagahisa Yoshimura
Format: Article
Language:English
Published: Elsevier 2018-02-01
Series:Heliyon
Subjects:
Ophthalmology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844017314445

Internet

http://www.sciencedirect.com/science/article/pii/S2405844017314445

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