Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma
Retinal neuronal cell death underlies many incurable eye diseases such as retinitis pigmentosa (RP) and glaucoma, and causes adult blindness. We have shown that maintenance of ATP levels via inhibiting ATP consumption is a promising strategy for preventing neuronal cell death. Here, we show that bra...
Main Authors: | Tomoko Hasegawa, Hanako Ohashi Ikeda, Sachiko Iwai, Yuki Muraoka, Tatsuaki Tsuruyama, Keiko Okamoto-Furuta, Haruyasu Kohda, Akira Kakizuka, Nagahisa Yoshimura |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-02-01
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Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844017314445 |
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