Alternate transcripts expressed in response to diet reflect tissue-specific regulation of ABCA1

Alternate transcripts expressed in response to diet reflect tissue-specific regulation of ABCA1

ABCA1 is essential for the transport of lipids across plasma membranes and for the maintenance of plasma HDL-cholesterol levels. The transcriptional regulation of ABCA1 is complex and is currently poorly understood. We previously generated human ABCA1 bacterial artificial chromosome transgenic mice...

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Bibliographic Details
Main Authors: Roshni R. Singaraja, Erick R. James, Jennifer Crim, Henk Visscher, Alu Chatterjee, Michael R. Hayden
Format: Article
Language:English
Published: Elsevier 2005-10-01
Series:Journal of Lipid Research
Subjects:
mouse model
liver
macrophage
high density lipoprotein
atherosclerosis
high-fat diet
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520328972

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http://www.sciencedirect.com/science/article/pii/S0022227520328972

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