Functional cell phenotype induction with TGF-β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair

Functional cell phenotype induction with TGF-β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair

Appropriate cell sources, bioactive factors and biomaterials for generation of functional and integrated annulus fibrosus (AF) tissue analogues are still an unmet need. In the present study, the AF cell markers, collagen type I, cluster of differentiation 146 (CD146), mohawk (MKX) and smooth muscle...

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Bibliographic Details
Main Authors: J Du, RG Long, T Nakai, D Sakai, LM Benneker, G Zhou, B Li, D Eglin, JC Iatridis, M Alini, S Grad, Z Li
Format: Article
Language:English
Published: AO Research Institute Davos 2020-01-01
Series:European Cells & Materials
Subjects:
annulus fibrosus
annular rupture repair
tissue engineering
transforming growth factor β1
polyurethane scaffold
Online Access:https://www.ecmjournal.org/papers/vol039/pdf/v039a01.pdf

Internet

https://www.ecmjournal.org/papers/vol039/pdf/v039a01.pdf

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