3-N-Butylphthalide (NBP) Attenuates the Amyloid-ß-Induced Inflammatory Responses in Cultured Astrocytes via the Nuclear Factor-κB Signaling Pathway

3-N-Butylphthalide (NBP) Attenuates the Amyloid-ß-Induced Inflammatory Responses in Cultured Astrocytes via the Nuclear Factor-κB Signaling Pathway

Background/Aims: Activation of astrocytes is a common feature of Alzheimer's disease (AD). Proinflammatory molecules produced by activated astrocytes contribute to neuronal damage in AD. Moreover, dl-3-n-butylphthalide (NBP) has been reported to attenuate astroglial activation and exert neuropr...

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Bibliographic Details
Main Authors: Hong-Mei Wang, Ting Zhang, Jian-Kang Huang, Xiao-Jiang Sun
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-07-01
Series:Cellular Physiology and Biochemistry
Subjects:
Nuclear factor-kappa B
Astrocyte
Amyloid β-peptide
Dl-3-n-butylphthalide
Inflammatory response
Online Access:http://www.karger.com/Article/FullText/350139

Internet

http://www.karger.com/Article/FullText/350139

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