Propionibacterium acnes induces cartilaginous endplate degeneration by promoting MIF expression via the NF-κB pathway

Abstract Background Propionibacterium acnes (P. acnes) is a novel pathogenic factor that contributes to cartilaginous endplate (CEP) degeneration. However, the underlying mechanism of P. acnes-induced CEP degeneration remains unclear. The objective of this study is to investigate the underlying mech...

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Bibliographic Details
Main Authors: Ying Zhang, Yuting Wang, Yanyan Yuan, Yeting Lin, Binbin Lin, Haiyan Zhou
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13018-020-01714-6