DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease – a multicentre RCT

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) is the commonest cause of dementia. Cholinesterase inhibitors, such as donepezil, are the drug class with the best evidence of efficacy, licensed for mild to moderate AD, while the glutamate antagonist m...

Full description

Bibliographic Details
Main Authors: Lindesay James, Knapp Martin, Jones Roy, Johnson Tony, Jacoby Robin, Hughes Alan, Holmes Clive, Griffin Mary, Gray Richard, Findlay David, Dening Tom, Burns Alistair, Brown Richard, Bentham Peter, Barber Bob, Banerjee Sube, Ballard Clive, Adams Jessica, Baldwin Ashley, Juszczak Ed, Phillips Patrick, Sheehan Bart, Jones Rob, McKeith Ian, McShane Rupert, Macharouthu Ajay, O'Brien John, Onions Caroline, Passmore Peter, Raftery James, Ritchie Craig, Howard Rob
Format: Article
Language:English
Published: BMC 2009-07-01
Series:Trials
Online Access:http://www.trialsjournal.com/content/10/1/57