Mutations of residues 249 and 256 in VP2 are involved in the replication and virulence of infectious Bursal disease virus.

Infectious bursal disease virus (IBDV) is a pathogen of worldwide significance to the poultry industry. Although the PDE and PFG domains of the capsid protein VP2 contribute significantly to virulence and fitness, the detailed molecular basis for the pathogenicity of IBDV is still not fully understo...

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Bibliographic Details
Main Authors: Xiaole Qi, Lizhou Zhang, Yuming Chen, Li Gao, Guan Wu, Liting Qin, Yongqiang Wang, Xiangang Ren, Yulong Gao, Honglei Gao, Xiaomei Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3724781?pdf=render