Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro.

Hypoxic preconditioning was shown to improve the therapeutic efficacy of bone marrow-derived multipotent mesenchymal stromal cells (MSCs) upon transplantation in ischemic tissue. Given the interest in clinical applications of umbilical cord blood-derived MSCs, we developed a specific hypoxic precond...

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Bibliographic Details
Main Authors: Andreas Matthäus Bader, Kristin Klose, Karen Bieback, Dirk Korinth, Maria Schneider, Martina Seifert, Yeong-Hoon Choi, Andreas Kurtz, Volkmar Falk, Christof Stamm
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4575058?pdf=render