Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial

Safety, tolerability, clinical, and joint structural outcomes of a single intra-articular injection of allogeneic mesenchymal precursor cells in patients following anterior cruciate ligament reconstruction: a controlled double-blind randomised trial

Abstract Background Few clinical trials have investigated the safety and efficacy of mesenchymal stem cells for the management of post-traumatic osteoarthritis. The objectives of this pilot study were to determine the safety and tolerability and to explore the efficacy of a single intra-articular in...

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Bibliographic Details
Main Authors: Yuanyuan Wang, Andrew Shimmin, Peter Ghosh, Paul Marks, James Linklater, David Connell, Stephen Hall, Donna Skerrett, Silviu Itescu, Flavia M. Cicuttini
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Arthritis Research & Therapy
Subjects:
Mesenchymal precursor cells
Anterior cruciate ligament reconstruction
Pain
Function
Cartilage
Subchondral bone
Online Access:http://link.springer.com/article/10.1186/s13075-017-1391-0

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http://link.springer.com/article/10.1186/s13075-017-1391-0

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