Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase-3 signaling pathway by upregulating miR-181b expression in rats

Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase-3 signaling pathway by upregulating miR-181b expression in rats

Abstract Background In China, Panax notoginseng has been used to treat oxidative stress-related diseases for a long time. Panax notoginseng saponins is an extract from Panax notoginseng Ledeb. Its therapeutic potential is related to antioxidant activity, but related mechanisms are still unclear. The...

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Bibliographic Details
Main Authors: Ming-wei Liu, Rui Wei, Mei-xian Su, Hui Li, Tian-wen Fang, Wei Zhang
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Acute pancreatitis
Panax notoginseng saponins
miR-181b
Taurocholate
Rat
Online Access:http://link.springer.com/article/10.1186/s12906-018-2118-8

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http://link.springer.com/article/10.1186/s12906-018-2118-8

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