Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisomerase IV Inhibitors
To develop new antimicrobial agents, a series of novel thiourea derivatives incorporated with different moieties <b>2–13</b> was designed and synthesized and their biological activities were evaluated. Compounds <b>7a</b>, <b>7b</b> and <b>8</b> exhibi...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-06-01
|
| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/25/12/2766 |