Integration of enzyme constraints in a genome-scale metabolic model of Aspergillus niger improves phenotype predictions

Integration of enzyme constraints in a genome-scale metabolic model of Aspergillus niger improves phenotype predictions

Abstract Background Genome-scale metabolic model (GSMM) is a powerful tool for the study of cellular metabolic characteristics. With the development of multi-omics measurement techniques in recent years, new methods that integrating multi-omics data into the GSMM show promising effects on the predic...

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Bibliographic Details
Main Authors: Jingru Zhou, Yingping Zhuang, Jianye Xia
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Microbial Cell Factories
Subjects:
Genome-scale metabolic model
Proteome constraint GSMM
Aspergillus niger
Differential expression of enzymes
Online Access:https://doi.org/10.1186/s12934-021-01614-2

Internet

https://doi.org/10.1186/s12934-021-01614-2

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