MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts

MiR-181a Targets PHLPP2 to Augment AKT Signaling and Regulate Proliferation and Apoptosis in Human Keloid Fibroblasts

Background/Aims: Keloids are fibrous overgrowths induced by cutaneous injury. MicroRNAs (miRNAs) have recently emerged as post-transcriptional gene repressors and participants in a diverse array of pathophysiological processes leading to skin disease. The purpose of the current study was to explore...

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Bibliographic Details
Main Authors: Zhen Rang, Zong-yang Wang, Qiu-yu Pang, You-wei Wang, Ge Yang, Fan Cui
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
miR-181a
PHLPP2
AKT
Keloid fibroblasts
Proliferation
Apoptosis
Online Access:http://www.karger.com/Article/FullText/453139

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http://www.karger.com/Article/FullText/453139

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