Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73

Abstract Background Metastasis is the leading cause of death in breast cancer patients. CD73, also known as ecto-5′-nucleotidase, plays a critical role in cancer development including metastasis. The existing researches indicate that overexpression of CD73 promotes growth and metastasis of breast ca...

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Bibliographic Details
Main Authors: Xu Yang, Shimin Pei, Huanan Wang, Yipeng Jin, Fang Yu, Bin Zhou, Hong Zhang, Di Zhang, Degui Lin
Format: Article
Language:English
Published: BMC 2017-04-01
Series:BMC Cancer
Subjects:
Thf
Online Access:http://link.springer.com/article/10.1186/s12885-017-3250-4