Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

Plasma Ceramides as Prognostic Biomarkers and Their Arterial and Myocardial Tissue Correlates in Acute Myocardial Infarction

Summary: We identified a plasma signature of 11 C14 to C26 ceramides and 1 C16 dihydroceramide predictive of major adverse cardiovascular events in patients with acute myocardial infarction (AMI). Among patients undergoing coronary artery bypass surgery, those with recent AMI, compared with those wi...

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Main Authors: Leonardo P. de Carvalho, MD, PhD, Sock Hwee Tan, PhD, Ghim-Siong Ow, BSc, Zhiqun Tang, PhD, Jianhong Ching, PhD, Jean-Paul Kovalik, MD, PhD, Sock Cheng Poh, BSc, Chee-Tang Chin, MBBS, A. Mark Richards, MD, PhD, Eliana C. Martinez, MD, PhD, Richard W. Troughton, MD, PhD, Alan Yean-Yip Fong, MBBS, Bryan P. Yan, MBBS, Aruni Seneviratna, MBBS, MPH, Vitaly Sorokin, MD, PhD, Scott A. Summers, PhD, Vladimir A. Kuznetsov, PhD, SciD, Mark Y. Chan, MBBS, PhD
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X18300056

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http://www.sciencedirect.com/science/article/pii/S2452302X18300056

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