Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells

Klotho is regulated by transcription factor Sp1 in renal tubular epithelial cells

Abstract Background Klotho is a multifunctional protein, which exists both in a membrane bound and a soluble form. In renal tubules, Klotho is involved in cell senescence, anti-oxidant response, and renal fibrosis, thus regulation of its expression is critical to understand its roles in renal diseas...

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Bibliographic Details
Main Authors: Yan Li, Yong Liu, Kailong Wang, Yinghui Huang, Wenhao Han, Jiachuan Xiong, Ke Yang, Mingying Liu, Tangli Xiao, Chi Liu, Ting He, Xianjin Bi, Jingbo Zhang, Bo Zhang, Jinghong Zhao
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Molecular and Cell Biology
Subjects:
Sp1
Klotho
Transcriptional regulation
Renal tubular epithelial cells
Online Access:http://link.springer.com/article/10.1186/s12860-020-00292-z

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http://link.springer.com/article/10.1186/s12860-020-00292-z

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