Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression

Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression

FOXF1 heterozygous point mutations and genomic deletions have been reported in newborns with the neonatally lethal lung developmental disorder, alveolar capillary dysplasia with misalignment of pulmonary veins (ACDMPV). However, no gain-of-function mutations in FOXF1 have been identified yet in any...

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Bibliographic Details
Main Authors: Avinash V. Dharmadhikari, Jenny J. Sun, Krzysztof Gogolewski, Brandi L. Carofino, Vladimir Ustiyan, Misty Hill, Tadeusz Majewski, Przemyslaw Szafranski, Monica J. Justice, Russell S. Ray, Mary E. Dickinson, Vladimir V. Kalinichenko, Anna Gambin, Paweł Stankiewicz
Format: Article
Language:English
Published: The Company of Biologists 2016-11-01
Series:Biology Open
Subjects:
Lung development
Pulmonary vasculature
ACDMPV
Online Access:http://bio.biologists.org/content/5/11/1595

Internet

http://bio.biologists.org/content/5/11/1595

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