Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis

Exosomes secreted by endothelial progenitor cells accelerate bone regeneration during distraction osteogenesis by stimulating angiogenesis

Abstract Background Distraction osteogenesis (DO) is an effective but lengthy procedure to fully induce bone regeneration in large bone defects. Accumulating evidence supports the role of exosomes secreted by endothelial progenitor cells (EPC-Exos) in stimulating angiogenesis, which is closely coupl...

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Bibliographic Details
Main Authors: Yachao Jia, Yu Zhu, Shuo Qiu, Jia Xu, Yimin Chai
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Stem Cell Research & Therapy
Subjects:
Distraction osteogenesis
Exosomes
Endothelial progenitor cells
Bone regeneration
Angiogenesis
Online Access:http://link.springer.com/article/10.1186/s13287-018-1115-7

Internet

http://link.springer.com/article/10.1186/s13287-018-1115-7

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