Ginsenosides Rk1 and Rg5 inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition and suppress migration, invasion, anoikis resistance, and development of stem-like features in lung cancer

Ginsenosides Rk1 and Rg5 inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition and suppress migration, invasion, anoikis resistance, and development of stem-like features in lung cancer

Background: Lung cancer has a high incidence worldwide, and most lung cancer-associated deaths are attributable to cancer metastasis. Although several medicinal properties of Panax ginseng Meyer have been reported, the effect of ginsenosides Rk1 and Rg5 on epithelial-mesenchymal transition (EMT) sti...

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Bibliographic Details
Main Authors: Hyunhee Kim, Pilju Choi, Taejung Kim, Youngseok Kim, Bong Geun Song, Young-Tae Park, Seon-Jun Choi, Cheol Hee Yoon, Won-Chul Lim, Hyeonseok Ko, Jungyeob Ham
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of Ginseng Research
Subjects:
Epithelial-mesenchymal transition
Ginsenosides
Lung cancer
Panax ginseng Meyer
Transforming growth factor β1
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845320300622

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http://www.sciencedirect.com/science/article/pii/S1226845320300622

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