Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections

Mechanistic Insights in the Success of Fecal Microbiota Transplants for the Treatment of Clostridium difficile Infections

Fecal microbiota transplantation has proven to be an effective treatment for infections with the gram-positive enteropathogen Clostridium difficile. Despite its effectiveness, the exact mechanisms that underlie its success are largely unclear. In this review, we highlight the pleiotropic effectors t...

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Bibliographic Details
Main Authors: Amoe Baktash, Elisabeth M. Terveer, Romy D. Zwittink, Bastian V. H. Hornung, Jeroen Corver, Ed J. Kuijper, Wiep Klaas Smits
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
fecal microbiota transplant
Clostridium difficile infection
short chain fatty acids
bile acids
sialic acids
antimicrobial peptides
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01242/full

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https://www.frontiersin.org/article/10.3389/fmicb.2018.01242/full

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