Low Dose BMP2-Doped Calcium Phosphate Graft Promotes Bone Defect Healing in a Large Animal Model

Low Dose BMP2-Doped Calcium Phosphate Graft Promotes Bone Defect Healing in a Large Animal Model

Background: Bone grafts are in high demand due to the increase in the cases of bone defects mainly caused by trauma, old age, and disease-related bone damages. Tissue-engineered calcium phosphate (CaP) biomaterials match the major inorganic contents of bone, thereby could be the potential bone graft...

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Bibliographic Details
Main Authors: Tie Liu, Wen Fang, Gang Wu, Yining Li, Janak L. Pathak, Yuelian Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
bone regeneration
BioCaP graft
BMP2
osteoinduction
bone defect healing
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.613891/full

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https://www.frontiersin.org/articles/10.3389/fcell.2020.613891/full

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