Targeting senescent cells in translational medicine

Abstract Organismal ageing is a complex process driving progressive impairment of functionality and regenerative potential of tissues. Cellular senescence is a state of stable cell cycle arrest occurring in response to damage and stress and is considered a hallmark of ageing. Senescent cells accumul...

Full description

Bibliographic Details
Main Authors: Marta Paez‐Ribes, Estela González‐Gualda, Gary J Doherty, Daniel Muñoz‐Espín
Format: Article
Language:English
Published: Wiley 2019-12-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.201810234