Aquaporin-3 Attenuates Oxidative Stress-Induced Nucleus Pulposus Cell Apoptosis Through Regulating the P38 MAPK Pathway

Aquaporin-3 Attenuates Oxidative Stress-Induced Nucleus Pulposus Cell Apoptosis Through Regulating the P38 MAPK Pathway

Background/Aims: Previous studies have shown that oxidative damage is a main contributor to disc nucleus pulposus (NP) cell apoptosis. Aquaporin-3 (AQP-3) facilitates reactive oxygen species (ROS) scavenging and thus alleviates oxidative injury in other cells. This study aims to investigate the role...

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Bibliographic Details
Main Authors: Yichun Xu, Hui Yao, Qiyou Wang, Wenbin Xu, Kaihua Liu, Junbin Zhang, Huiqing Zhao, Gang Hou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Nucleus pulposus
Apoptosis
Aquaporin-3
Oxidative damage
Online Access:https://www.karger.com/Article/FullText/494788

Internet

https://www.karger.com/Article/FullText/494788

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