A TRPV channel modulates C. elegans neurosecretion, larval starvation survival, and adult lifespan.

For most organisms, food is only intermittently available; therefore, molecular mechanisms that couple sensation of nutrient availability to growth and development are critical for survival. These mechanisms, however, remain poorly defined. In the absence of nutrients, newly hatched first larval (L1...

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Bibliographic Details
Main Authors: Brian H Lee, Kaveh Ashrafi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2556084?pdf=render