Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?

Highly Elevated Serum Hepcidin in Patients with Acute Myeloid Leukemia prior to and after Allogeneic Hematopoietic Cell Transplantation: Does This Protect from Excessive Parenchymal Iron Loading?

Hepcidin is upregulated by inflammation and iron. Inherited (HFE genotype) and treatment-related factors (blood units (BU), Iron overload) affecting hepcidin (measured by C-ELISA) were studied in 42 consecutive patients with AML prior to and after allogeneic hematopoietic cell transplantation (HCT)....

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Bibliographic Details
Main Authors: Ann-Kathrin Eisfeld, Mark Westerman, Rainer Krahl, Sabine Leiblein, Uwe Gerd Liebert, Marianne Hehme, Daniel Teupser, Dietger Niederwieser, Haifa Kathrin Al-Ali
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2011/491058

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http://dx.doi.org/10.1155/2011/491058

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