Doxorubicin-induced myocardial failure in rats with malignant neoplasm: Protective role of fullerenol C60(OH)24

Doxorubicin-induced myocardial failure in rats with malignant neoplasm: Protective role of fullerenol C60(OH)24

The therapeutic utility of the anthracycline antibiotic doxorubicin is limited due to its cardiotoxicity. Our aim was to investigate the efficacy of fullerenol C60(OH)24 in preventing single, high-dose doxorubicin-induced cardiotoxicity in rats with malignant neoplasm. In vitro and in vivo studies h...

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Bibliographic Details
Main Authors: Injac Rade, Đorđević Aleksandar N., Štrukelj Borut
Format: Article
Language:English
Published: Association of Chemical Engineers of Serbia 2008-01-01
Series:Hemijska Industrija
Subjects:
cardioprotection
doxorubicin
fullerenol
oxidative stress
heart
rats
mammary carcinomas
Online Access:http://www.doiserbia.nb.rs/img/doi/0367-598X/2008/0367-598X0803197I.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0367-598X/2008/0367-598X0803197I.pdf

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