Distribution of Menin-Occupied Regions in Chromatin Specifies a Broad Role of Menin in Transcriptional Regulation

Distribution of Menin-Occupied Regions in Chromatin Specifies a Broad Role of Menin in Transcriptional Regulation

Menin is the protein product of the MEN1 tumorsuppressor gene; one allele of MEN1 is inactivated in the germ line of patients with “multiple endocrine neoplasia type 1” (MEN1) cancer syndrome. Menin interacts with several proteins involved in transcriptional regulation. RNA expression analyses have...

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Bibliographic Details
Main Authors: Sunita K. Agarwal, Soren Impey, Shannon McWeeney, Peter C. Scacheri, Francis S. Collins, Richard H. Goodman, Allen M. Spiegel, Stephen J. Marx
Format: Article
Language:English
Published: Elsevier 2007-02-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
MEN1
multiple endocrine neoplasia
SACO
chromatin immunoprecipitation
ChIP
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860780039X

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http://www.sciencedirect.com/science/article/pii/S147655860780039X

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