Impact of Fibronectin Knockout on Proliferation and Differentiation of Human Infrapatellar Fat Pad-Derived Stem Cells

Impact of Fibronectin Knockout on Proliferation and Differentiation of Human Infrapatellar Fat Pad-Derived Stem Cells

Fibronectin plays an essential role in tissue development and regeneration. However, the effects of fibronectin knockout (FN1-KO) on stem cells' proliferation and differentiation remain unknown. In this study, CRISPR/Cas9 generated FN1-KO in human infrapatellar fat pad-derived stem cells (IPFSC...

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Bibliographic Details
Main Authors: Yiming Wang, Yawen Fu, Zuoqin Yan, Xiao-Bing Zhang, Ming Pei
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
fibronectin
infrapatellar fat pad-derived stem cell
proliferation
chondrogenic differentiation
adipogenic differentiation
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2019.00321/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2019.00321/full

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