In vitro inhibitory effects of ganoderic acid A on human liver cytochrome P450 enzymes

Context Ganoderic acid A (GAA) is usually used to prevent cancers or other diseases, which make it likely to be used with other drugs metabolized by cytochromes P450. Objective This study investigates the effect of GAA on eight major cytochrome P450 isoforms in human liver microsomes. Material and m...

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Bibliographic Details
Main Authors: Shangchen Xu, Fengqing Zhang, Dali Chen, Keren Su, Li Zhang, Rui Jiang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Pharmaceutical Biology
Subjects:
Online Access:http://dx.doi.org/10.1080/13880209.2020.1747500