Combination of LCZ696 and ACEI further improves heart failure and myocardial fibrosis after acute myocardial infarction in mice

Combination of LCZ696 and ACEI further improves heart failure and myocardial fibrosis after acute myocardial infarction in mice

Background: LCZ696, an angiotensin receptor–neprilysin inhibitor (ARNi), is reported to play a cardioprotective role after acute myocardial infarction (AMI). Angiotensin-converting enzyme inhibitors(ACEIs) have similar roles. However, it is unclear whether the combination of the two drugs has a bett...

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Bibliographic Details
Main Authors: Youbin Liu, Ying Fan, Jinglong Li, Meng Chen, Anyong Chen, Dahao Yang, Xue Guan, Yong Cao
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Biomedicine & Pharmacotherapy
Subjects:
LCZ696
ACEI
Myocardial infarction
Combination therapy
Cardiac function
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220310179

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http://www.sciencedirect.com/science/article/pii/S0753332220310179

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