Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice

Inhibition of HDAC6 alleviating lipopolysaccharide-induced p38MAPK phosphorylation and neuroinflammation in mice

Context: Researchers in a variety of fields have extensively focused on histone deacetylase 6 (HDAC6) due to its aggravation of inflammatory reaction. However, relevant studies examining whether HDAC6 could exacerbate lipopolysaccharide (LPS)-induced inflammation are still lacking. Objective: We ass...

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Bibliographic Details
Main Authors: Yuanjian Song, Li Qin, Rongli Yang, Fan Yang, Nwobodo Alexander Kenechukwu, Xiaofang Zhao, Xiaoyan Zhou, Xiangru Wen, Lei Li
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Pharmaceutical Biology
Subjects:
histone deacetylase 6
tubastatin a
inflammation
phosphorylated p38mapk
Online Access:http://dx.doi.org/10.1080/13880209.2018.1563620

Internet

http://dx.doi.org/10.1080/13880209.2018.1563620

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