Synthetic libraries of shark vNAR domains with different cysteine numbers within the CDR3.

The variable domain of New Antigen Receptors (vNAR) from sharks, present special characteristics in comparison to the conventional antibody molecules such as: small size (12-15 kDa), thermal and chemical stability and great tissue penetration, that makes them a good alternative source as therapeutic...

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Bibliographic Details
Main Authors: Olivia Cabanillas-Bernal, Salvador Dueñas, Marta Ayala-Avila, Alexandra Rucavado, Teresa Escalante, Alexei F Licea-Navarro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0213394