h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy

h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy

Ih tunes hippocampal CA1 pyramidal cell dendrites to optimally respond to theta inputs (4–12 Hz), and provides a negative time delay to theta inputs. Decreased Ih activity, as seen in experimental temporal lobe epilepsy (TLE), could significantly alter the response of dendrites to theta inputs. Here...

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Bibliographic Details
Main Authors: Béatrice Marcelin, Laëtitia Chauvière, Albert Becker, Michele Migliore, Monique Esclapez, Christophe Bernard
Format: Article
Language:English
Published: Elsevier 2009-03-01
Series:Neurobiology of Disease
Subjects:
Epilepsy
HCN channel
Dendrite
Theta rhythm
Resonance
Oscillation
Online Access:http://www.sciencedirect.com/science/article/pii/S096999610800301X

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http://www.sciencedirect.com/science/article/pii/S096999610800301X

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