Triglyceride mobilization from lipid droplets sustains the anti-steatotic action of iodothyronines in cultured rat hepatocytes.

Triglyceride mobilization from lipid droplets sustains the anti-steatotic action of iodothyronines in cultured rat hepatocytes.

Adipose tissue, dietary lipids and de novo lipogenesis are sources of hepatic fatty acids (FFAs) that are stored in lipid droplets (LDs) as triacylglycerols (TAGs). Destiny of TAGs stored in LDs is determined by LD proteomic equipment. When adipose triglyceride lipase (ATGL) localizes at LD surface...

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Bibliographic Details
Main Authors: Elena eGrasselli, Adriana eVoci, Ilaria eDemori, Giulia eVecchione, Andrea D Compalati, Gabriella eGallo, Fernando eGoglia, Rita eDe Matteis, Elena eSilvestri, Laura eVergani
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-01-01
Series:Frontiers in Physiology
Subjects:
Iodothyronines
lipid droplet
Adipose triglyceride lipase
primary cultured rat hepatocytes
in vitro steatosis
lipid lowering action
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00418/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00418/full

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