Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa.

Surface attachment, an early step in the colonization of multiple host environments, activates the virulence of the human pathogen P. aeruginosa. However, the downstream toxins that mediate surface-dependent P. aeruginosa virulence remain unclear, as do the signaling pathways that lead to their acti...

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Bibliographic Details
Main Authors: Geoffrey D Vrla, Mark Esposito, Chen Zhang, Yibin Kang, Mohammad R Seyedsayamdost, Zemer Gitai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008867