Construction of a Chimeric Secretory IgA and Its Neutralization Activity against Avian Influenza Virus H5N1
Secretory immunoglobulin A (SIgA) acts as the first line of defense against respiratory pathogens. In this assay, the variable regions of heavy chain (VH) and Light chain (VL) genes from a mouse monoclonal antibody against H5N1 were cloned and fused with human IgA constant regions. The full-length c...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2014-01-01
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Series: | Journal of Immunology Research |
Online Access: | http://dx.doi.org/10.1155/2014/394127 |