Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer

Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer

Background: The establishment of patient-derived models for pancreatic ductal adenocarcinoma (PDAC) using conventional methods has been fraught with low success rate, mainly because of the small number of tumour cells and dense fibrotic stroma. Here, we sought to establish patient-derived model of P...

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Bibliographic Details
Main Authors: Hee Seung Lee, Eunyoung Kim, Jinyoung Lee, Seung Joon Park, Ho Kyoung Hwang, Chan Hee Park, Se-Young Jo, Chang Moo Kang, Seung-Mo Hong, Huapyong Kang, Jung Hyun Jo, In Rae Cho, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Jung Min Han, Sangwoo Kim, Seungmin Bang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:EBioMedicine
Subjects:
Pancreatic ductal adenocarcinoma
Conditionally reprogrammed cell lines
Next-generation sequencing
Patient-derived cancer cell line
Precision medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000116

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http://www.sciencedirect.com/science/article/pii/S2352396421000116

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