Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis.

Downregulation of TNIP1 Expression Leads to Increased Proliferation of Human Keratinocytes and Severer Psoriasis-Like Conditions in an Imiquimod-Induced Mouse Model of Dermatitis.

Psoriasis is a chronic, inflammatory skin disease involving both environmental and genetic factors. According to genome-wide association studies (GWAS), the TNIP1 gene, which encodes the TNF-α-induced protein 3-interacting protein 1 (TNIP1), is strongly linked to the susceptibility of psoriasis. TNI...

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Bibliographic Details
Main Authors: Yan Chen, Heng Yan, Zhiqiang Song, Fangru Chen, Huan Wang, Jun Niu, Xiaowei Shi, Dongmei Zhang, Na Zhang, Zhifang Zhai, Baiyu Zhong, Liangjin Cheng, Tian Qian, Fei Hao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4457880?pdf=render

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http://europepmc.org/articles/PMC4457880?pdf=render

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