Methodology for prediction of anticancer action of (2-oxo-2H-[1,2,4]¬triazino[2,3-c]-quinazolin-6-yl)thiones via QSAR and docking studies
Aimed to elaborate new group of protein kinase inhibitors we conducted receptor-based screening (docking, QSAR modeling) and biochemical testing for derivatives of (2-oxo-2H-[1,2,4]triazino[2,3-c]quinazolin-6-yl)thiones. Methods and results. This study allowed identifying of new potential antican...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Zaporozhye State Medical University
2015-02-01
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Series: | Zaporožskij Medicinskij Žurnal |
Subjects: | |
Online Access: | http://zmj.zsmu.edu.ua/article/view/39873/36005 |