Fluorescence in situ hybridization patterns of BCR/ABL1 fusion in chronic myelogenous leukemia at diagnosis

Fluorescence in situ hybridization patterns of BCR/ABL1 fusion in chronic myelogenous leukemia at diagnosis

Background : Chronic myelogenous leukemia (CML) is characterised by the t(9;22)(q34;q11.2) which results in the formation of the BCR/ABL1 fusion gene. Occasionally, the t(9;22) may be associated with submicroscopic deletions of chromosomes 9 and/or 22 which appear to be associated with a worse progn...

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Bibliographic Details
Main Authors: Poonam P Jain, Mayur Parihar, Rayaz Ahmed, Aby Abraham, Auro Vishwabandya, Biju George, Vikram Mathews, Alok Srivastava, Vivi M Srivastava
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Chronic myelogenous leukemia
BCR/ABL1 fusion
atypical FISH signals
Online Access:http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=3;spage=347;epage=351;aulast=Jain

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http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2012;volume=55;issue=3;spage=347;epage=351;aulast=Jain

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