Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer

Antitumor Therapy under Hypoxic Microenvironment by the Combination of 2-Methoxyestradiol and Sodium Dichloroacetate on Human Non-Small-Cell Lung Cancer

A hypoxic microenvironment is a hallmark in different types of tumors; this phenomenon participates in a metabolic alteration that confers resistance to treatments. Because of this, it was proposed that a combination of 2-methoxyestradiol (2-ME) and sodium dichloroacetate (DCA) could reduce this alt...

Full description

Bibliographic Details
Main Authors: Yair Romero, Manuel Castillejos-López, Susana Romero-García, Alfonso Salgado Aguayo, Iliana Herrera, Misael O. Garcia-Martin, Luz Maria Torres-Espíndola, Maria Cristina Negrete-García, Angel Camarena Olvera, Juan Carlos Huerta-Cruz, Rafael Velázquez-Cruz, José Cisneros, Edgar Flores Soto, Héctor Solís-Chagoyán, Criselda Mendoza-Milla, Carlos Cabello-Gutiérrez, Víctor Ruiz, Arnoldo Aquino-Gálvez
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2020/3176375

Internet

http://dx.doi.org/10.1155/2020/3176375

Similar Items