Antifungal Activity and Potential Mechanism of Panobinostat in Combination With Fluconazole Against Candida albicans

Antifungal Activity and Potential Mechanism of Panobinostat in Combination With Fluconazole Against Candida albicans

Invasive fungal infections are an emerging problem worldwide, which bring huge health challenges. Candida albicans, the most common opportunistic fungal pathogen, can cause bloodstream infections with high mortality in susceptible hosts. At present, available antifungal agents used in clinical pract...

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Bibliographic Details
Main Authors: Shan Su, Xiaohong Shi, Wei Xu, Yiman Li, Xueqi Chen, Shuang Jia, Shujuan Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
fluconazole
panobinostat
synergy
histone deacetylase inhibitor
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01584/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01584/full

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