α-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton
α-Synuclein is a primarily neuronal protein that is enriched at the pre-synapse. α-Synuclein and the microtubule binding protein tau have been implicated in neurodegenerative diseases. α-Synuclein is known to associate with phospholipid vesicles, regulates dopamine metabolism and exhibits chaperone...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2007-06-01
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| Series: | Neurobiology of Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996107000277 |