Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors

Basal Forebrain Volume, but Not Hippocampal Volume, Is a Predictor of Global Cognitive Decline in Patients With Alzheimer's Disease Treated With Cholinesterase Inhibitors

Background: Predicting the progression of cognitive decline in Alzheimer's disease (AD) is important for treatment selection and patient counseling. Structural MRI markers such as hippocampus or basal forebrain volumes might represent useful instruments for the prediction of cognitive decline....

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Bibliographic Details
Main Authors: Stefan J. Teipel, Enrica Cavedo, Harald Hampel, Michel J. Grothe, Alzheimer's Disease Neuroimaging Initiative, Alzheimer Precision Medicine Initiative (APMI)
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Neurology
Subjects:
cholinergic treatment
MRI
prediction
memory
executive function
basal forebrain
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00642/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00642/full

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